Fingert Lab NewsThursday, March 12, 2020 - 15:30
Lab discovers first genetic risk factor for glaucoma that is unique to patients with African AncestryFingert Lab NewsWednesday, November 6, 2019 - 10:45
The Fingert and Mullins Labs collaborated with investigators from Duke University, Singapore, and from around the world to identify the first genetic risk factor for glaucoma that is unique to people with African ancestry - a population group with highest prevalence of glaucoma and most severe disease. Notably, the newly identified glaucoma risk factor, APBB2, has important links with the biology of another degenerative condition, Alzheimer’s disease. This major advance in glaucoma research was published in the Journal of the American Medical Association.
Fingert Lab NewsMonday, October 7, 2019 - 16:30
Grad student Carly van der Heide has successfully defended her PHD thesis describing her work in the Anderson and Fingert labs. She returns to medical school and will graduate with an MD and PHD in May 2021.
Fingert Lab NewsMonday, September 23, 2019 - 13:45
Medical Student Josh Hagedorn’s research on the genetics of nanophthalmos was presented at the Carver College of Medicine Student Medical Research Conference and was recognized for excellence with the Hansjoerg E. Kolder Award.
Fingert Lab NewsWednesday, June 5, 2019 - 10:15
Large populations of patients were analyzed to search for correlations between features of glaucoma (intraocular pressure corneal thickness) and features of diabetes (fasting blood sugar, fasting insulin, and hemoglobin A1c). No clinical or genetic correlations between diabetes and glaucoma related traits were detected. Read more about this research here.
Fingert Lab NewsThursday, February 28, 2019 - 15:15
In a collaborative study with investigators from Iowa and from the NEIGHBORHOOD consortium the Glaucoma Genetics Lab reports that MYOC mutations are one of the most common, known-causes of normal tension glaucoma, glaucoma that occurs with normal to low intraocular pressure. Read more about the report here.
Fingert Lab NewsFriday, January 25, 2019 - 10:30
Exfoliation syndrome is a leading cause of glaucoma worldwide. However, progress in developing better therapies for exfoliation glaucoma has been hindered by the lack of an animal model. Dr. John Fingert and Dr. Michael Anderson have received a two-year, $418,000 research award from the National Eye Institute to create and study animal models of exfoliation glaucoma using a genome editing approach.
Fingert Lab NewsThursday, January 10, 2019 - 16:00
Post-doctoral fellow in the Glaucoma Genetics Lab, Ankur Jain, has been awarded a $50,000 Shaffer Grant for his proposal, "Autophagy-targeted Treatment for Myocilin-associated Glaucoma”. These funds will support his research to determine how gene-defects cause optic nerve damage and glaucoma.
Fingert Lab NewsWednesday, January 9, 2019 - 09:00
Dr. Fingert discusses myocilin mutations and how likely they are to cause glaucoma in an invited commentary in JAMA Ophthalmology. Read more about it here.
Fingert Lab NewsThursday, October 4, 2018 - 15:00
We conducted the first ever analysis of an eye donated for research from a patient with glaucoma caused by a myocilin mutation. Our study of this eye shows how myocilin mutations may cause glaucoma. We detected abnormal accumulation of myocilin protein within the cells of the eye that regulate eye pressure. (trabecular meshwork cells). Ultimately this abnormality may cause eye pressure to rise and lead to glaucoma. Read more about this report here.